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Vertical dashed lines represent a 2-fold change (FC) threshold, while horizontal dashed lines denote a p -value threshold of 0.05

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Therefore, pro-apoptotic proteins can be activated and anti-apoptotic proteins can be suppressed by calcitriol/VDR signaling, which may also reduce tumor-associated inflammation by suppressing the cyclooxygenase-2, prostaglandin, and NF-kB pathways

Komes, and N