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Without regulatory oversight, products sold as Epitalon may vary considerably in purity, peptide content, and contamination

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If you have been at a dose that previously produced noticeable appetite suppression and that effect suddenly disappears, potency loss is a possible explanation

Shu L., Yang M., Liu N., et al., Short Hexapeptide Optimized From RiceDerived Peptide 1 Shows Promising AntiHyperuricemia Activities, Journal of Agricultural and Food Chemistry 70 (2022): 66796687, 10.1021/acs.jafc.2c00354