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BRIEF DESCRIPTION OF THE DRAWINGS Figure 1A, B, and C

Phase 3 Standard Cagrilintide Dose Based on Phase 2 findings, the standard cagrilintide dose for Phase 3 trials was established at: 2.4 mg administered subcutaneously once weekly This dose represents the optimal balance between: Efficacy : Substantial weight loss and metabolic improvements Safety : Manageable side effect profile Tolerability : Acceptable patient adherence rates The REDEFINE 1 trial, which evaluated cagrilintide in combination with semaglutide (CagriSema), used this 2.4 mg dose and demonstrated remarkable results

showed that FOXO4 expression is upregulated in irradiated-induced senescent IMR90 cells and that the protein binds to p53, inhibiting the role of this last one in apoptosis induction

It aims to quickly fill up the bodys stores and keep levels right