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By inhibiting NNMT, 5-Amino-1MQ preserves SAM availability and reduces SAH accumulation, potentially supporting proper methylation of DNA, histones, and proteins - epigenetic modifications that regulate gene expression and cellular function

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Common applications include: Obesity and Body-Weight Regulation Models : Studying how chronic exposure to AOD 9604 affects body weight, fat, and energy use in obese rodents, often using calorimetry (measuring energy expenditure) and body fat measurements