This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily
Many people find that taking glutathione on an empty stomach, or about 20 minutes before a meal, helps with absorption
References: Thomas, A., Walpurgis, K., Delahaut, P., Fichant, E., Schnzer, W., & Thevis, M
Increases in NAD+ promote cognitive and sensory function, gluconeogenesis in the liver, lipogenesis in adipose tissue, insulin secretion in the pancreas, and insulin sensitivity in muscle