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Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells

Human adult dermal fibroblasts incubated with GHK-Cu at concentrations of 0.01, 1, and 100 nM demonstrated increased production of both elastin and collagen, with all concentrations increasing TIMP1 expression and low concentrations enhancing MMP1 and MMP2 gene expression

Guthikonda, et al

This three-pathway anti-inflammatory profile makes the blend of particular interest for research models where systemic or localized inflammatory signaling is the study endpoint, as investigators can evaluate the combined effect against individual component controls