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Bilirubin interacted directly with mitochondria, affecting membrane lipid and protein characteristics, redox status, and cytochrome C concentration, and bilirubin-induced apoptosis may be mediated in part by physical changes in the mitochondrial membrane

Aloe preparations e.g., sap or powder, are useful as emollients, purgatives, a vulnerary agent, tonic, demulcent, vermifuge, antifungal, emmenagogue

Research explores whether this decline contributes to age-related tissue changes and whether replenishment in research models can reverse aging biomarkers

Precaution: Pregnant, lactating and individuals with a history of medical conditions are required to consult a physician prior to use