glutathione and cancer stem cell Human cancer-associated fibroblasts enhance levels antagonize drug-induced prostate death A study shows that the

Among these elements is also glutathione (GSH), which plays a very interesting multifunctional role

Cellular GSH is found mostly in the cytosol, with the remainder spread across organelles ( The thioredoxin system is composed of Trx proteins and Trx reductases (TrxR), in which the reduced form of Trx proteins (Trx(SH) 2 ) are disulfide reductases as they contain dithiol groups in their highly conserved active site (-Cys-Gly-Pro-Cys-) ( 2 can directly reduce oxidized proteins or provide electrons to thiol-dependent peroxidases (Prx) to convert hydrogen peroxide to water

Priya AS, Afzal O, Khalid M, Faruque Ahmad M, Upadhyay A, Kumar S, Garg A, Ramzan M, Hussain A, et al

Kelesidis, T., et al