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A Nrf2 activator, Sulforaphane (SFN), augmented Prdx6, catalase and GST expression in dose-dependent fashion, and halted Nrf2 dysregulation of these antioxidants

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Low brain GABA is also associated with insomnia people with long-term primary insomnia average about 30% lower GABA and with reduced cortical GABA in major depression

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