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One theory behind methylene blues cognitive boosting abilities has to do with the high concentration of mitochondria in your brain and how the solution affects it

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de Luna N, Carbayo , Dols-Icardo O, Turon-Sans J, Reyes-Leiva D, Illan-Gala I, Jeric I, Pagola-Lorz I, Lleix C, Querol L, Rubio-Guerra S, Alcolea D, Fortea J, Lle A, Corts-Vicente E, Rojas-Garcia R (2022) Neuroinflammation-related proteins NOD2 and Spp1 are abnormally upregulated in amyotrophic lateral sclerosis

This accumulation may interact with central neurotransmitter systems, thereby contributing to the characteristic behavioral and cognitive symptoms of ASD (DSM-5, 2013