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oral melanotic macules

oral melanotic macules Pigmented lesions of the cavity: An Update Differential Diagnosis of Pigmented Lesions

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Description

I was intrigued when I came across a study of people with Down syndrome (who are known to have thyroid issues as they age), that suggested folate supplements helped with preventing thyroid issues

oral melanotic macules Pigmented lesions of the cavity: An Update Differential Diagnosis of Pigmented Lesions

doi:10.1210/endocr/bqz046

oral melanotic macules Pigmented lesions of the cavity: An Update Differential Diagnosis of Pigmented Lesions

Methionine is then converted into S-adenosylmethionine (SAM), which donates methyl groups in reactions catalyzed by methyltransferases, including DNA methylation, producing S-adenosylhomocysteine (SAH) that is converted back into homocysteine

oral melanotic macules Pigmented lesions of the cavity: An Update Differential Diagnosis of Pigmented Lesions

CoQ10, magnesium, B vitamins (especially B1, B2, B3, and B5), iron, copper, and alpha-lipoic acid are all cofactors in the energy production pathway

oral melanotic macules Pigmented lesions of the cavity: An Update Differential Diagnosis of Pigmented Lesions
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