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Peter Lurie, a former FDA official who now leads the Center for Science in the Public Interest

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While steady progress has been made in the understanding of NAFL/NASH pathophysiology and identification of therapeutic targets, relatively slow progress was achieved in the treatment of all aspects of NAFL/NASH even after years of intense research, 5,13,45 although several approved drugs for treating metabolic-related disorders and diseases showed promising outcomes in patients with NAFL/NASH, including Orlistat 46 used for the treatment of obesity (Fig

Pourebrahim R , Khanna P, Yang D, Muftuoglu M, Ostermann LB, Khazaei S, Zhao R, Asare A, Hajek RA, Lee S, Corvingo S, Gagea M, Sood A, Li R, Takahashi K, Andreeff M