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Caution must also be exercised at 3 fingerbreadths, or approximately 2 inches (5.08 cm), below the acromion process since the axillary nerve has been identified to be at risk of puncture injury with injections made at this location

Mastocytosis: Systemic or Cutaneous Mastocytosis is a condition caused by a proliferation of mast cells due to too many being created and released in the bone marrow

There may also be minor irritation at the injection site,for example, redness, tenderness, or a brief burning sensation where the NAD+ solution is injected subcutaneously