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CNMN NMN 4

Complicated cases involve abscess, fistula, bowel obstruction, or perforation, all of which require hospitalisation and sometimes surgery

Other (less serious) concerns are if EGF can properly penetrate the skin (as it is a medium-sized, polar molecule, so a special delivery system is probably needed), if it can affect collagen synthesis (or just works on the surface plumping up only the upmost layers of the skin) and if it has beneficial effects at all when used in isolation versus when used in a "conditioned media" that contains lots of growth factors resembling the synergistic balance found in the skin

Vitamins used in the IVs are water soluble, so once your body uses whats needed, it will excrete the excess through your kidneys into your urine