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[72] In 1907, Richard Clarke Cabot reported on a series of 1,200 patients with PA

USA 114 , 50955100 (2017)

Oxidative stress in Egyptian children with autism: relation to autoimmunity

176 Collectively, these advances underscore a fundamental conceptual shift: proteostasis must now be viewed not as a collection of isolated degradation mechanisms but as a coherent, adaptive, and deeply integrated cellular defense network whose resilience determines disease trajectory