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Figure 3 3 Roles of ferroptosis in the pathogenesis of renal diseases 3.1 Revisiting the distinctive link between ferroptosis and acute kidney disease Ischemiareperfusion (I/R) is a common cause of AKI, often occurring in kidney transplantation, shock, trauma, and urological and cardiovascular surgeries

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We then found that downregulation of CSE sensitized cells to ferroptosis (Fig