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NF-B, a transcription factor closely associated with the inflammatory response, has the capacity to induce the transcription of various inflammatory factors and contribute to the development of inflammation [109]

Amano Y, Tsuchiya S, Imai M, Tohyama K, Matsukawa J, Isono O, Yasuno H, Enya K, Koumura E, Nagabukuro H (2018) Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis

There was one death in each of the certolizumab pegol treatment arms, one due to a myocardial infarction, and one due to sudden death of unknown cause