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The mice were housed in micro-isolator cages under a 12-h light/dark cycle with free access to food and water, in compliance with protocols reviewed and approved by the Institutional Animal Care and Use Committee of Keimyung University (KM2023-017)

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Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled, dose-finding phase 2 trial

In clinical trials, retatrutide at higher doses showed mean heart rate increases that exceeded those seen with tirzepatide