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18(2):185 Multifunctionality and possible medical application of the BPC 157 peptide: literature and patent review Seiwerth S, Rucman R, Turkovic B, et al., Current Pharmaceutical Design , 2018

This situation would lead to a self-perpetuating cycle, in which the free radicals generated would induce GSH depletion, thus increasing oxidative stress that would reduce antioxidant enzyme levels, which would further reduce GSH synthesis