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304 As migratory/invasive cancer cells specifically prefer mitochondrial respiration and increased ATP production, it is not surprising that invasive cancer cells boost OXPHOS, mitochondrial biogenesis, and the oxygen consumption rate by enhancing PGC-1 to perform functional motility of cancer cells and metastasis

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Activated CD8+ T cells treated ex vivo with simultaneous inhibition of A2AR and lipid peroxidation acquire a superior capacity to proliferate and persist in vivo, demonstrating a translatable means to prevent ferroptosis in adoptive cell therapy

The panel's vote is not binding but is likely to embolden Health Secretary Robert F