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Originally described from White patients of northern European ancestry and North Americans, autoimmune hepatitis is now recognized to occur worldwide

In patients whose symptoms are refractory to rigorously implemented conservative therapy, the key surgical options are sacral neuromodulation, sphincteroplasty, some implantable biomaterials and, as a final resort, colonic stoma

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How TB-500 Works TB-500 acts through a single, structurally well-defined biochemical activity: 1:1 sequestration of monomeric (G-) actin via the conserved LKKTETQ alpha-helix preserved in the 17-mer