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This compound is currently in phase 1 clinical evaluation in patients with advanced solid malignancies or non-Hodgkins lymphoma (NHL) (clinicaltrials.gov

Ryu JK, Kim SJ, Rah SH et al (2017) Reconstruction of LPS transfer cascade reveals structural determinants within LBP, CD14, and TLR4-MD2 for efficient LPS recognition and transfer

Abstract Resistance to apoptosis in acute myeloid leukemia (AML) cells causes refractory or relapsed disease, associated with dismal clinical outcomes

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