it builds volumetric density throughout the entire dermis
NR4A1 inhibits the ubiquitination degradation of P53 by regulating the downstream target gene MDM2, thereby affecting the oxidative respiration process of mitochondria, producing oxidized lipids, and inducing ferroptosis in cells
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doi: 10.3389/fnut.2026.1779855 Received 02 January 2026 Revised 02 February 2026 Accepted 19 February 2026 Published 04 March 2026 Volume 13 - 2026 Edited by Karolina Wojtunik-Kulesza, Medical University of Lublin, Poland Reviewed by Changhao He, Zhejiang Chinese Medical University, China Adriano Dos Santos, University of Bern, Switzerland Updates Copyright 2026 Pinaffi-Langley, Zuraikat, St-Onge and Yabluchanskiy