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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

That candor is part of why patients keep coming back to this treatment

Topical protocols deliver the peptide directly to dermal tissue at the application site, achieving high local concentrations without systemic distribution

In animal studies, AOD-9604 treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity in adipose tissue