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10.1016/j.freeradbiomed.2004.02.075 Free Radic

In addition, compared to cytotrophoblasts (CTBs), STBs exhibit a reduced capacity for antioxidant activity, diminished mitochondrial respiration, and altered metabolic processes

Preliminary animal studies show that exercise in high-fat diet mice resulted in reduced hepatic 4-HNE levels and upregulation of anti-apoptotic protein expression (Merry and Ristow, 2016)