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Nicotinamide promotes neuronal differentiation of mouse embryonic stem cells in vitro
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Similarly, dehydroabietic acid ameliorated high-fat diet-induced NAFLD by triggering Nrf2, elevating the levels of GSH, HO-1, and GPX4 for attenuating the accumulation of ROS and lipid peroxide MDA, subsequently suppressing hepatic ferroptosis (Gao et al., 2021)
Glycyrrhizin inhibits the metabolism of diosbulbin B (Yang et al., 2024), promotes bile acid efflux by increasing the expression of Nrf2/Farnesoid X Receptor- Bile Salt Export Pump (FXR-BSEP)/Multidrug Resistance-Associated Protein (MRP)2/P-glycoprotein/UDP-glucuronosyltransferase 1A1(UGT1A1), modulates gut microbiota, alleviates inflammation and oxidative stress, and improves diosbulbin B-induced liver injury (Wang et al., 2025)
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