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This very recent experimental evidence demonstrated in zebrafish highlights that polystyrene microplastics (PS-MPs) are widespread pollutants in aquatic environments and that they may accumulate in various organs, including the brain, raising concerns about their neurotoxic effects, enacted mainly through neuroinflammation

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Scenario 1: significant weight loss (50 or more pounds to lose) Starting point: BMI 35+, 50 to 100+ pounds above healthy weight range