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COVIDinduced inflammation and immune dysregulation appear to destabilize immune control over latent EBV, allowing reactivation that may contribute to Long COVID symptomatology

A 1999 study (PMID: 10373343) showed increased longitudinal bone growth (tibial length) with no significant change in bone turnover markers (osteocalcin, BSAP)suggesting growth through increased bone volume rather than remodeling

This capability is particularly critical in serious illness communication, where effective care requires a nuanced understanding of patients' values and beliefs about end-of-life treatment