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In fact, the use of GSTP1 knockout mice demonstrated that loss of GSTP1 expression increases sensitivity to metabolic or environmental toxins and promotes mutations and cancer development (Coughlin and Hall, 2002a,b)

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Numerous clinical studies have shown that regular physical exercise can significantly improve insulin sensitivity by promoting the translocation of glucose transporter proteins to the cell membrane in skeletal muscle cells, thus enhancing glucose uptake and utilization in peripheral tissues (Liu et al., 2023)