In humans, using proton magnetic resonance spectroscopy ( 1 H-MRS), ketamine administration has been found to acutely increase anterior cingulate cortex (ACC) glutamate 8 , glutamine 9 and glutamate + glutamine (Glx) 10 in healthy volunteers, and to increase Glx in the mPFC in patients with MDD 11
In our study, intracellular ROS levels and ferrous ion concentrations, which are key facilitators of the Fenton reaction, were significantly elevated following cystine treatment
The chloroplastic DHAR activity was not affected, whereas the mitochondrial and peroxisomal DHAR activities were distinctly decreased starting from the third day after pathogen challenge
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