Increased risks of heart attacks: Hormone treatments (e.g., testosterone) increase the risk of heart attack, stroke, and blood clots.Cancer risk: Long-term use of growth hormone or sex hormones may raise the risk of certain cancers (e.g., breast, prostate).Mood changes: Hormone imbalance can lead to mood swings, anxiety, or depression.Illegal use: Some medications, like human growth hormone (HGH), are illegal for anti-ageing use and carry legal risks.Poor regulation of compounded drugs: Compounded drugs are not a standardised product, appear to carry some risk of contamination, possibly present in the wrong dosage, and potentially contain harmful additives.No proven long-term benefit: Many anti-ageing treatments show little or only temporary benefit, and the long-term safety of such treatments is unknown.Misleading marketing: Treatments are often marketed with claims that greatly exceed any support from scientific research.Also read | Struggling with weak nails

AsarnowJRBaraffLJBerkMGrobCDevich-NavarroMSuddathRet alPediatric emergency department suicidal patients: two-site evaluation of suicide ideators, single attempters, and repeat attempters
doi: 10.1016/j.cell.2016.10.043 80 KhanSWaliullahSGodfreyVKhanMAWRamachandranRACantarelBLet al
Conclusions and perspectives Although prior reviews have laid important groundwork in understanding the transcriptional and epigenetic control of autophagy, most notably the foundational contributions by Fllgrabe et al