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In an Alzheimers disease model using scopolamine-induced amnesia in rats, Dihexa significantly improved spatial memory

These include using biodegradable backbones or enzymatically cleavable linkers, surface neutralization (for example hydroxylation, carboxylation or PEGylation) to reduce cationic surface reactivity, minimizing generation/size for dendrimers while preserving targeting, and requiring chronic-dosing safety packages that measure persistent microglial activation and behavioral outcomes before first-in-human trials

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Effects of omega-3 polyunsaturated fatty acids and their metabolites on haemostasis-current perspectives in cardiovascular disease