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Vitamin C contributes to normal collagen formation for the normal function of skin

Periwinkle contains vincamine, a compound that improves microcirculation and blood flow in the periocular capillaries reducing the pooled blood that makes dark circles visible through thin under-eye skin

Tryptamine produced by bacterial decarboxylation of dietary tryptophan accelerates gastrointestinal transit by activating the epithelial G-protein-coupled receptor (GPCR) serotonin receptor-4 (5-HT 4 R) and increasing anion-dependent fluid secretion in the proximal colon (Bhattarai et al., 2018)