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The results of the current randomized, double-blind, placebo-controlled clinical trial demonstrated that oral administration of l-ARG at the dose of 6 g/day for 3 months significantly improved penile erectile function assessed by IIEF-6 score and PSV evaluated at dynamic PDU in 50 male patients with vasculogenic ED, compared to 45 placebo-treated patients

Notably, pathological iron accumulation has been consistently observed in the hippocampus and cortical regions of AD patients

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