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The complexities arise from Section 503A of the Federal Food, Drug, and Cosmetic Act, which relates to the necessary conditions for drug compounding.20 The rules concerning the compounding of therapeutic peptides state that they must come from accredited compounding pharmacies, and the compounded drug must either be compounded from an existing FDA-approved drug product or use drug products included on the 503A bulks list (i.e., the FDAs roster of compoundable substances.)21 But many therapeutic peptides dont satisfy either of the 503A conditions

Liu et al., Estrogen Affects the Cellular Metabolism of the Anterior Cruciate Ligament, The American journal of sports medicine 25, no

10.1126/science.1151839 Science 249 WattB.van NielG.RaposoG.MarksM