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The site of obstruction may be at the level of small hepatic venules, large hepatic veins, or the inferior vena cava

The prescribed frequency and dosage vary from peptide to peptide

However, like -cells, the likely redundancy of diuretic-sensitive mechanisms involved in the regulation of hepatocyte [Cl ] i makes it challenging to study the role of loop diuretics on hepatic glucose metabolism

doi: 10.3389/fimmu.2025.1547992 Received 19 December 2024 Accepted 02 May 2025 Published 26 May 2025 Volume 16 - 2025 Edited by Omowumi Adewale, Osun State University, Nigeria Reviewed by Gopal Patel, Lakshmi Narain College of Pharmacy, India Miguel Pereira-Silva, University of Texas MD Anderson Cancer Center, United States Updates Copyright 2025 Deng, Wei, Han, Li, Xu, Zhang and Zhang