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The exact absorption rate is hard to predict, but this sustained release should help maintain steadier blood levels of B12

First described back in the 1950s, acne erupts in about one in ten people within days or even hours of getting an injection of vitamin B12, which then disappears rapidly when injection treatment is discontinued. At the time, we had no idea what the mechanism might be, and the problem remained unsolved until just a few years ago when we finally figured it out: Vitamin B12 modulates the gene expression of the skin bacteria that cause acne

Tolerance has not been observed in clinical use

Documentation may be required to prove necessity