free iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5- or 3- UTRs of the mRNAs
In the context of breast cancer, both ellagic acid and curcumin, natural polyphenolic compounds, have been highlighted for their role in regulating oxidative stress to restore cellular equilibrium and protect against oxidative-stress-induced cell injury (Golmohammadi et al
GHK Cu has powerful cytoprotective effects, such as a variety of anti-cancer activities and anti-inflammatory effects, lung protection and recovery of chronic obstructive pulmonary disease (COPD) fibroblasts, inhibition of molecules thought to accelerate aging diseases, such as NFB, anti-aging, anxiety, anti-pain and anti-attack activity, DNA repair and activation of cell cleansing through the proteasome system
F.DislerR.OrdmanR.GoodwinA.et al
