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278 In an MCD-induced mouse NASH model, vitamin E supplementation reduced hepatic inflammation and fibrosis by reducing the expression of the proapoptotic BCL2-related X (BAX), TGF-dead, cyclooxygenase-2 (COX-2), and matrix metalloproteinase-2 (MMP-2)

None of these ranges come from a published human clinical trial of IGF-1 LR3 they are extrapolated from preclinical work, the Increlex (mecasermin) clinical record, and decades of community reporting

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