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We demonstrate here that MCs, histamine, and H4R coordinate to promote innate immunemediated immunopathology and damage associated with mucosal inflammation in colitis

On the one hand, BBB penetration can be improved through the structural modification of small molecules [173], finally increasing brain exposure

PMID: 109 Al-ShuhaibMBSAl-ShuhaibJMB

Oncolytic CVA21 production was scaled-up 75-fold from the laboratory scale and demonstrated across seven batches in 250 L single-use microcarrier bioreactors and purified with customized, prepacked, single-use 1.5 L GSH affinity chromatography columns