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Those with asthma should also exercise caution as there are anecdotal reports (mostly with inhaled glutathione) of it triggering asthma attacks in susceptible individuals

doi: 10.1186/s12929-020-00679-2 122 ToledoM

Although the direct cytotoxic effects of high cellular GSSG levels have been documented in a variety of cell types 33,34,35,36 , our cell culture studies with hepatocytes revealed that increased GSSG accumulation, despite being non-toxic per se, could sensitize hepatocytes to TNF-induced killing, suggesting that GSSG and TNF can synergistically induce hepatocyte death and that GSSG-triggered sensitization to TNF hepatotoxicity represents a clinically relevant process that may account for disease progression in NAFLD

Circulating levels of VEGF and CXCL1 are predictive of metastatic organotropismin in patients with colorectal cancer