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,, Although there are several inhibitors of the cystine/glutamate transporter other than sulfasalazine, these drugs have limitations of low bioavailability and low selectivity to of the cystine/glutamate transporter in vivo

The combination of dysregulated lipid homeostasis and impaired purine metabolism may offer a mechanistic explanation for the similar symptoms observed in ME/CFS and GWS

Red flags that need care Seek urgent medical help if sleep problems come with chest pain, trouble breathing, fainting, confusion, hallucinations, seizure, severe agitation, suicidal thoughts, or a serious allergic reaction

For now, they remain powerful tools in the hands of educated researchers pushing the boundaries of what is possible in recovery