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Even the mainstay of any vitamin regimen, vitamin C, becomes less bioavailable with increased doses, especially above 250 mg.1 For example, taking either 1 or 2 grams of powdered vitamin C will yield similar blood levels, as the majority of vitamin C will pass through the body

However, in controlled therapeutic settings, ozone therapy has demonstrated calculated oxidative stress induction, which activates therapeutic benefits without resulting in acute or chronic toxicity [29]