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In the human ciliary epithelium, vitamin C uptake from the stroma is mediated by the Na + dependent vitamin C transporter, SVCT2 [74] which was shown to be expressed in the PE [13]

Under some pathophysiological circumstances, endothelium-derived vasoconstricting factors, such as ET-1, AT-II, urotensin II, superoxide anions, vasoconstrictor prostaglandins and thromboxane A 2 , can be released and contribute to the paradoxical vasoconstrictor effects

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