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Additionally, the reduced plasma levels of brain-derived neurotrophic factor (BDNF) observed in BIPN patients may be associated with BTZ-mediated inhibition of platelet aggregation and activation, which in turn leads to decreased BDNF release and consequently impairs its neuroregenerative effects on peripheral nerves (Nishiwaki et al., 2020)

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While sermorelin is generally considered safe and well tolerated, men considering this therapy should know the possible risks and how to minimize them