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Several GST isozymes from various classes have been shown to inhibit the function of a kinase involved in the MAPK pathway that regulates cell proliferation and death, preventing the kinase from carrying out its role in facilitating the signaling cascade

Compound Overview Class of Compound: Peptide Mechanism of Action: N-Acetyl Selank Amidate passes through the blood-brain barrier and acts on the central nervous system by interacting with BDNF levels and opioid, serotonergic, and GABA signaling

Current areas of scientific investigation include oxidative stress research, cellular antioxidant studies, redox biology investigations, cellular defense mechanism research, metabolic pathway analysis, mitochondrial function studies, aging and longevity research, and cellular signaling investigations

They examined signaling pathway activity and EpCAM expression in a panel of 31 epithelial cancer cell lines