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Category 2 of the Bulk Substances Nominated Under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act Park MG, Yeo JK, Park SG, Na W, Moon DG

When B12 levels rise, the bacteria stop making their own B12 and instead begin producing more porphyrins compounds that trigger inflammation in the skin and can lead to breakouts

(PubMed) Zhou J, Sun Y, Ji M, Li X, Wang Z

Reconstitution Protocol: Solvent: Sterile bacteriostatic water or appropriate buffer Technique: Add solvent slowly along vial wall Mixing: Gently swirl until dissolveddo not shake or vortex (shear forces damage peptide bonds) Sterility: Maintain aseptic conditions throughout Post-Reconstitution Storage: 2-8C: Use within 4 weeks Aliquot and freeze at -20C for extended storage Avoid repeated freeze-thaw cycles Protect from light and moisture The 3-Tier Storage Protocol STABLE - Prewritten Phase (Up to 4 Months) Unreconstituted lyophilized peptides remain chemically stable at room temperature (15-25C) for 3-4 months when stored away from direct sunlight and moisture