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It usually presents in infancy with a severe phenotype including failure to thrive, weakness, anemia and pancytopenia, and requires life-long treatment with high doses of vitamin B12 (37)

Although there are some research studies on the effects of natural products on NDs, the antioxidant mechanism of dietary antioxidant supplements in this process has not been deeply explored, and there are few systematic summaries on preclinical and clinical data

Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes

10.3390/ijms20020252 211 VargheseS.PramanikS.WilliamsL