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Science 179 , 588590 (1973)

It remains an investigational compound available only through clinical trial participation

2.5.2 Covariate model The influence of potential covariates on tacrolimus PK variability, including age, sex, height, body weight (WT), fat-free mass, grafted hepatic weight, hematocrit (HCT), albumin (ALB), aspartate aminotransferase (AST), total serum bilirubin (TBIL), creatinine clearance, POD, concomitant medications, and CYP3A5*3, CYPP3A4*1G, SUMO4, and NR112 genetic polymorphisms in both donors and recipients, was investigated

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