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The rationale is straightforward: a 120kg individual has significantly more tissue volume for the peptide to distribute through than a 70kg individual, which affects both the effective concentration at receptor sites and the perceived intensity of side effects

While some claim that B12 injections can boost metabolism and aid in weight loss, research does not support these claims in individuals without a deficiency

I was purchasing B-12 filled needles exact dose from my vet prior to this

In addition, Cyp7a1-overexpressing transgenic mice have been reported to show improved glucose tolerance and reduced G6pc expression under HFD condition 24